Vitamin D is a fat soluble family of compounds known as vitamins D1, D2
and D3. It is obtained from food, and, uniquely among the vitamins, it can be
created in the
skin through the action of sunlight.
What does it do for your body?
The biologically active form of vitamin D is a hormone known as
calcitriol.
Bone - The most important role of vitamin D is to regulate the absorption and use of
calcium and phosphorus, vital for normal growth and development of bones and
teeth. Vitamin D stimulates intestinal absorption and reabsorption in the kidneys as well
as maintaining blood levels of calcium and phosphorus. It enables bones and teeth to
harden by increasing the deposition of calcium and may also assist in the movement of
calcium across body cell membranes.
Immune System - Vitamin D may also be involved in immune system regulation and play a
part in the prevention and treatment of infectious diseases. Parts of the bone marrow
which produce immune cells are receptive to vitamin D.
Fertility - Vitamin D is essential for strong pelvic bones and therefore plays an indirect
role in fertility.
Hormones - Vitamin D plays a role in the secretion of insulin by the pancreas thus aiding
in the regulation of blood sugar. It also affects the parathyroid gland and a hormone that
it produces due to its calcium regulating role.
Nervous System - Vitamin D ensures the functioning of healthy nerves and muscles by
regulating the level of calcium in the blood. Calcium is vital for normal nerve impulse
transmission and muscle contraction.
Absorption
When taken orally, vitamin D is absorbed with fat through the intestinal walls. Vitamin D
can be stored the fat cells of the liver, skin, brain and bones in amounts sufficient for
many months. Exposure to sunlight in spring, summer and autumn makes up for
any shortfall in dietary vitamin D and even short exposure to sunlight during these times
is adequate, although there may be problems in winter months in some climates. Babies under
12 months have stores of vitamin D which they accumulate while in the womb.
The production of vitamin D in the body is blocked by anything which blocks ultraviolet
light including skin pigment, smog, fog, sunscreen, windows and hats.
Deficiency
In cases of vitamin D deficiency the body increases production of a hormone that removes
calcium from the bones. In children, this results in rickets where the bones are so soft
that they become curved from supporting the weight of the body. The equivalent in adults
is osteomalacia with bone pain and tenderness and muscle weakness.
Other signs of deficiency include hearing loss (due to a softening of the bones
in the inner ear), senile osteoporosis (where the bones become lighter and less dense) and
severe tooth decay.
Older people may be at risk of vitamin deficiency since they do not absorb or manufacture
vitamin D in their bodies as well as younger people. Others at risk of deficiency include
alcoholics, people who don’t drink milk or get much sunlight, those with fat
absorption problems and darker skinned people living in colder climates. Vitamin D is
converted in the liver and kidneys to its active form so sufferers of kidney and liver
diseases may also be at risk of vitamin D deficiency.
Therapeutic uses
Vitamin D is recommended to support bone health in postmenopausal women.
Vitamin D may also be of benefit in the control of psoriasis.
Interactions
Cholestyramine and mineral oil and may interfere with the absorption of vitamin D. Alcohol
interferes with the conversion of vitamin D to its biologically active form.
Pantothenic acid is necessary for the synthesis of vitamin D.
People taking certain anti-epileptic drugs may develop a form of resistance to vitamin D.
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